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Lead Data Scientist Since 2003, this robotics company based in Center City Philadelphia has been developing 1 of the most sophisticated artificial intelligence platforms the world has ever seen. However, over the last few years the progression of their advancements has slowed down significantly. Right now, they are looking to hire a director of Data Science to initiate a new direction of the pr...
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Support development of next generation Antibody Drug Conjugates using both general and proprietary bioconjugation methodology. Activities: *** Synthesize, purify, and characterize new antibody drug conjugates and related biotherapeutic agents for production in microgram to gram scales. *** Perform antibody bioconjugation, characterization, and purification. *** Utilize synthetic, analytical and...
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Develop and advance projects for Antibody Drug Conjugates through preclinical and clinical stage. Functions: *** Advance development of multiple antibody drug conjugate programs. *** Apply Design of Experiments, Quality by Design, and Failure Modes and Effects Analysis principles to support process understanding, scale-up, and specification setting. *** Perform various analytical characterizati...
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Develop and validate assays in a laboratory setting. Must have background with optical and surface analysis methods such as: Dynamic Mechanical Analysis, Thermomechanical Analysis, Differential Scanning Calorimetry, Thermal Gravimetric Analysis, Residual Gas Analysis, X-ray Diffraction, Small Angle X-Ray Scattering, Differential Scanning Fluorimetry, Fourier-Transform Infrared Spectroscopy, Ram...
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Shall: *** Design, perform, and validate new protein analysis and characterization methods. *** Characterize protein stability and interactions. *** conduct assay process development, documentation, and scale up. *** Validate, troubleshoot, and test new assays. Methods and processes used include: *** Dynamic Mechanical Analysis *** Thermomechanical Analysis *** Differential Scanning Calorimetry...
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Support protein crystallization for development of sustained release and high concentration formulations of drug substances that are advancing into clinical trials for feasibility studies. Responsibilities: *** Design, execute and interpret results of experiments to develop low viscosity drug product formulations for crystalline protein slurries. *** Develop crystallization and scale up method ...
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Provide protein production and analytical and biophysical characterization of protein targets and reagents, and therapeutic and reagent antibodies, including molecular interactions using biosensors. Activities: *** Characterize protein structure, stability, and aggregation state using technologies such as microcalorimetry, fluorescence or other spectroscopy, light scattering, solubility assays,...
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Seeking professional with hands-on background with optical and surface analysis methods such as Dynamic Mechanical Analysis, Thermomechanical Analysis, Differential Scanning Calorimetry, Thermal Gravimetric Analysis, Residual Gas Analysis, X-ray Diffraction, Small Angle X-Ray Scattering, Differential Scanning Fluorimetry, Fourier-Transform Infrared Spectroscopy, Raman Spectroscopy, Scanning Ele...
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Lead efforts to design and validate assays, analyze and characterize proteins, protein stability, and protein interactions, and provide technical assistance where needed. Must be familiar with Dynamic Mechanical Analysis, Thermomechanical Analysis, Differential Scanning Calorimetry, Thermal Gravimetric Analysis, Residual Gas Analysis, X-ray Diffraction, Small Angle X-Ray Scattering, Differentia...
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Stuck in a laboratory all day? Want to do more than just process blood samples? If you have technical knowledge of the following instrumentation, this might be your ticket out of the lab! Leverage deep scientific knowledge to identify customer challenges and map them to company's products and services. Equipment: *** Blood Glucose Analyzers *** Automated Blood Gas Analyzers *** Blood Lactate Te...
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Support therapeutic virus program and oversee manufacture of clinical materials in compliance with current Good Manufacturing Practice (cGMP). *** Manage team of manufacturing associates for large scale production of virus drug substances and drug product. *** Improve recovery, throughput, and scalability to optimize viral product manufacturing process. *** Review, approve, and maintain process...
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Join Preclinical Research team at global drug company developing tumor-directed antibody-drug conjugates (ADCs) to conduct cross-functional research into the mechanisms of disease biology and drug actions and more specifically identify and validate novel chemotypes and antibody drug targets. Position focuses on assessing target modulation and its impact on cell viability and cell cycle disrupti...
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Support liquid chromatography-tandem mass spectrometry bioanalytical method development and validation; biological sample analysis; and in vitro and ex vivo drug metabolism studies. Activities: *** Design and oversee GLP-regulated bioanalytical method development, validation, and sample analysis. *** Conduct enzymatic assays and in vitro or ex vivo drug metabolism studies, including liver micro...
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Support large scale organic synthesis, biochemical processing, and purification techniques such as column chromatography and crystallizations. *** Oversee manufacturing of lipid Active Pharmaceutical Ingredients such as phospholipids, sphingolipids, sterols, and similar. *** Maintain, troubleshoot, and calibrate critical process equipment. *** Perform Installation Qualification and Operational ...
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Produce materials for use in immunology based chromatography and enzyme tests and critical and non-critical bioreagents for use in product and manufacturing processes. *** Maintain and support production schedule and ensure sufficient raw bioreagent supply. *** Perform in-process Quality Control testing of manufacturing materials as it relates to requirements, quality inspections, and titration...
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Manage production of synthetic oligonucleotides in a Good Manufacturing Practices environment for use in In Vitro diagnostic products. *** Oversee operation of automated synthesis equipment, High Performance Liquid Chromatography product purification, and similar. *** Prepare solutions and implement in-process analytical techniques. *** Develop validation protocols. *** Validate and maintain sp...
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Seeking background in bioconjugation, purification, and characterization of complex bioconjugates to produce novel antibody drug conjugates by participating in experimental design and planning, conducting experiments, maintaining detailed records, and communicating results. Responsibilities: *** Develop and optimize conjugation protocols utilizing novel chemistries and technologies. *** Perform...
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Position performs diagnostic and repair work, including scheduled preventative maintenance and necessary repairs to automobiles, trucks (light, medium, and heavy commercial/DOT-regulated vehicles), vans and forklifts. Position works with a high degree of independence. Position also requires a number of physical movements including lifting, pinching, bending, reaching, climbing, and manipulating...
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Seeking experienced bioanalytical scientist who can: Assess bioanalytical testing needs or research groups and develop methods to determine quantitative data sets on metabolized small-molecule compounds. QUALIFICATIONS: Thorough hands on background with LC-MS/MS; M.S. or Ph.D. in Chemistry, Biochemistry or equivalent; and 3+ years in Bioanalytical chemistry method development. ACTIVITIES: Colla...
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Clinical Laboratory Scientist II: Roxborough Memorial Hospital in Philadelphia, PA seeks a Clinical Lab Scientist II to adhere to lab processes to collect, process, analyze, and report patient test results, review accuracy of patient results, & perform wide variety of lab procedures. Mail Resume & ad copy to A. Stanam at 3300 E. Guasti Rd., Ontario, CA 91761. (PHC14)
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